Publications

Papers

  • Kim J, Amorim E, Rao VR, Glass HC, Bernardo D. Short-horizon neonatal seizure prediction using EEG-based deep learning. PLOS Digital Health. 2025 Jul 11;4(7):e0000890. PMID: 40644380
  • Lai GY, Sullivan JE, Numis AL, Singhal NS, Gonzalez-Giraldo E, Bernardo D, Auguste KI. Payer type and prediction of the time from epilepsy onset to neurosurgical intervention and from first diagnostic MRI to neurosurgical consultation in lesional drug-resistant epilepsy at a California level IV epilepsy center. Journal of Neurosurgery: Pediatrics. 2025 Jun 6;1(aop):1-2. PMID: 40479817
  • Kim J, Podlasek A, Shidara K, Liu F, Alaa A, Bernardo D. Limitations of large language models in clinical problem-solving arising from inflexible reasoning. arXiv preprint arXiv:2502.04381. 2025 Feb 5. Arxiv preprint.
  • Bernardo D, Kim J, Cornet MC, Numis AL, Scheffler A, Rao VR, Amorim E, Glass HC. Machine learning for forecasting initial seizure onset in neonatal hypoxic–ischemic encephalopathy. Epilepsia. 2025 Jan;66(1):89-103. PMID:39495029 
  • Yang S, Luo Y, Jiao M, Fotedar N, Rao VR, Ju X, Wu S, Xian X, Sun H, Karakis I, Bernardo D. EpiSemoLLM: A Fine-tuned Large Language Model for Epileptogenic Zone Localization Based on Seizure Semiology with a Performance Comparable to Epileptologists. MedRxiv. 2024 Sep 17:2024-09. 
  • Bernardo D, Xie X, Verma P, Kim J, Liu V, Numis AL, Wu Y, Glass HC, Yap PT, Nagarajan SS, Raj A. Simulation-based inference of developmental EEG maturation with the spectral graph model. Communications Physics. 2024 Jul 31;7(1):255. PMCID:12310519
  • Kim J, Glass HC, Amorim E, Rao VR, Bernardo D. Comparison of Feature Engineering and End-to-End Machine Learning for Neonatal Preictal State Classification. InInternational Pediatric and Lifespan Data Science Conference 2024 May 23 (pp. 17-30). Cham: Springer Nature Switzerland.
  • Kim JW, Alaa A, Bernardo D. EEG-GPT: exploring capabilities of large language models for EEG classification and interpretation. arXiv preprint arXiv:2401.18006. 2024 Jan 31.
  • Kim J, Glass HC, Amorim E, Rao VR, Bernardo D. Exploration of Short-range Neonatal Seizure Forecasting with Quantitative EEG Based Deep Learning. medRxiv. 2023 Aug 6:2023-08.
  • Miyakoshi M, Nariai H, Rajaraman RR, Bernardo D, Shrey DW, Lopour BA, Sim MS, Staba RJ, Hussain SA. Automated preprocessing and phase-amplitude coupling analysis of scalp EEG discriminates infantile spasms from controls during wakefulness. Epilepsy Research. 2021 Dec 1;178:106809.
  • Tremblay-Laganière C, Maroofian R, Nguyen TT, Karimiani EG, Kirmani S, Akbar F, Ibrahim S, Afroze B, Doosti M, Ashrafzadeh F, Babaei M. PIGG variant pathogenicity assessment reveals characteristic features within 19 families. Genetics in Medicine. 2021 Oct;23(10):1873-81.
  • Nariai H, Hussain SA, Bernardo D, Motoi H, Sonoda M, Kuroda N, Asano E, Nguyen JC, Elashoff D, Sankar R, Bragin A. Scalp EEG interictal high frequency oscillations as an objective biomarker of infantile spasms. Clinical Neurophysiology. 2020 Nov 1;131(11):2527-36.
  • Bernardo D, Nariai H, Hussain SA, Sankar R, Wu JY. Interictal scalp fast ripple occurrence and high frequency oscillation slow wave coupling in epileptic spasms. Clinical Neurophysiology. 2020 Jul 1;131(7):1433-43.
  • Nariai H, Hussain SA, Bernardo D, Fallah A, Murata KK, Nguyen JC, Rajaraman RR, Rao LM, Matsumoto JH, Lerner JT, Salamon N. Prospective observational study: Fast ripple localization delineates the epileptogenic zone. Clinical neurophysiology. 2019 Nov 1;130(11):2144-52.
  • Nariai H, Wu JY, Bernardo D, Fallah A, Sankar R, Hussain SA. Interrater reliability in visual identification of interictal high‐frequency oscillations on electrocorticography and scalp EEG. Epilepsia open. 2018 Dec;3:127-32.
  • Charupanit K, Nunez MD, Bernardo D, Bebin M, Krueger DA, Northrup H, Sahin M, Wu JY, Lopour BA. Automated detection of high frequency oscillations in human scalp electroencephalogram. In 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) 2018 Jul 18 (pp. 3116-3119). IEEE.
  • Bernardo D, Nariai H, Hussain SA, Sankar R, Salamon N, Krueger DA, Sahin M, Northrup H, Bebin EM, Wu JY, Group UP. Visual and semi-automatic non-invasive detection of interictal fast ripples: A potential biomarker of epilepsy in children with tuberous sclerosis complex. Clinical Neurophysiology. 2018 Jul 1;129(7):1458-66.
  • Bernardo DR, Chahin N. Toxoplasmic encephalitis during mycophenolate mofetil immunotherapy of neuromuscular disease. Neuroimmunology & Neuroinflammation. 2015 Jan 22;2(1):e63.
  • Pluta T, Bernardo R, Shin HW, Bernardo DR. Unsupervised learning of electrocorticography motifs with binary descriptors of wavelet features and hierarchical clustering. In 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society 2014 Aug 26 (pp. 2657-2660). IEEE.
  • Roberts AC, Díez-García J, Rodriguiz RM, López IP, Luján R, Martínez-Turrillas R, Picó E, Henson MA, Bernardo DR, Jarrett TM, Clendeninn DJ. Downregulation of NR3A-containing NMDARs is required for synapse maturation and memory consolidation. Neuron. 2009 Aug 13;63(3):342-56.
  • Yashiro, Koji, et al. "Ube3a is required for experience-dependent maturation of the neocortex." Nature neuroscience 12.6 (2009): 777-783.

Book Chapters

  • Bernardo D. Epilepsy in the RASopathies. In the RASopathies: Genetic Syndromes of the RAS/MAPK Pathway 2024 Nov 30 (pp. 635-651). Cham: Springer Nature Switzerland.